Different funders support different stages. The PRiSM siRNA trial is funded by NIH NeuroNEXT, and donations to the Prion Alliance cover participant travel. The CJD Foundation funds earlier work, including a 2025 grant to Gate Bioscience, in collaboration with the Broad Institute, to test whether an oral PrP-lowering compound extends survival in prion-infected mice. Companies carry the Ionis and Regeneron programs.
What is known is limited. No program has human safety and efficacy data, and the Ionis trial has said no public results before 2027. Gaps and timing are covered in gaps and the grant calendar, and how to give lists routes for donors. See also partners, AI and insurers.
Explore
- Funding gapsWhere prion disease research funding is documented, where it is thin, and what public sources do and do not show about money and stage.
- Grant calendarDates for the CJD Foundation 2026 to 2027 research grant and fellowship calls, with what is not known about other funders' calendars.
- How to support researchRoutes for donors and foundations to give to prion disease research and family support, with what each organisation publishes.