Christina D. Orru

NIAID scientist at Rocky Mountain Laboratories who first-authored the nasal brushing RT-QuIC test and led RT-QuIC training for outside laboratories.

Key facts

  • Lead author of the second-generation RT-QuIC paper (mBio 2015) and of the 2020 six-laboratory ring trial; staff scientist on Caughey's team for 19 years and trained people at about 30 laboratories.
  • First author of the 2014 NEJM nasal brushing RT-QuIC study (97 percent sensitivity and 100 percent specificity).
  • By 2019 she had trained people at about 30 laboratories on RT-QuIC, according to a tribute to Byron Caughey.
  • She is lead author with Groveman and Caughey of the 2025 chapter Tracking Prions by RT-QuIC: An Update.
  • She is named among the colleagues in Caughey's lab in 2019 and a co-contributor of the CWD rectal mucosa RT-QuIC protocol.
  • A named inventor on the NIH bank vole substrate technology listing (as Christina Groveman).

Timeline

  1. 2014NEJM nasal brushing paper.
  2. 2019Named in the RML team photo.
  3. 2025RT-QuIC update chapter online.

Institutions

Projects and trials

Research papers

Works with

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Last checked 16 October 2026

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